Motif Bio
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| Motif Bio PLC | |
|---|---|
| Type | Public |
| Industry | Biopharmaceuticals |
| Founded | 2014 |
| Headquarters | London, United Kingdom |
| Key people | Graham George Lumsden (CEO), David B. Huang (Chief Medical Officer), Robert Joseph Bertoldi [1] |
| Number of employees | 4 [2] |
We are a clinical stage biopharmaceutical company engaged in the research and development of novel antibiotics designed to be effective against serious and life-threatening infections in hospitalized patients caused by multi-drug resistant bacteria. [3] Its lead product candidate is Iclaprim, a novel antibiotic that is in Phase III clinical trials to treat bacterial infections, such as acute bacterial skin and skin structure infections, and hospital acquired bacterial pneumonia caused by methicillin-resistant staphylococcus aureus and multi-drug resistant streptococcus pneumoniae. [4]
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Iclaprim is a dihydrofolate reductase (DHFR) inhibitor originally discovered by F. Hoffman-La Roche Ltd. Iclaprim was licensed to and developed by Arpida AG.
Iclaprim is a potential novel antibiotic, designed to be effective against bacteria that have developed resistance to other antibiotics, including trimethoprim. Iclaprim exhibits potent activity against Gram-positive clinical isolates of many genera of staphylococci, including methicillin sensitive staphylococci (MSSA) and methicillin resistant staphylococci (MRSA).
[5]
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| Date | Author | Comment |
|---|---|---|
| November 24, 2021 | deadlyboy_ | Follow my new Instagram in bio https://t.co/XU1egVowqi |
| November 24, 2021 | PCP_EIC | Advance Access🚅: Regular Paper published online🖥️ 🌿🌱🧬WHIRLY1 of Barley and Maize share a PRAPP Motif conferring Nuc… https://t.co/fVeo5s6ZIr |
| November 24, 2021 | JDelrm | New set is up, link in bio. 😈 https://t.co/oRrq3fH7CI |
| November 24, 2021 | itsmebum2 | Link in bio ;) https://t.co/tLWJGoxEBs |
| October 12, 2021 | bywayofiker | Pillow talk, anyone? Link in bio for more! https://t.co/h1rHVo68BS |
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- ↑ https://www.motifbio.com/about/management-team/
- ↑ http://www.nasdaq.com/markets/ipos/company/motif-bio-plc-998919-81297
- ↑ http://www.nasdaq.com/markets/ipos/company/motif-bio-plc-998919-81297#ixzz4QjOzZx00
- ↑ http://www.bloomberg.com/research/stocks/private/snapshot.asp?privcapId=283471296
- ↑ https://www.motifbio.com/iclaprim/
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