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MicroConstants is a GLP-compliant Contract Research Organization focused on performing regulated bioanalysis, drug metabolism and pharmacokinetic analysis in support of discovery, preclinical and clinical drug development studies. They specialize in method development, validation and sample analysis for small molecules, macromolecules, biomarkers and metabolites using LC/MS/MS, HPLC/UV, immunoassay, multiplex and qPCR techniques. They also assembles and distributes protocol-specific specimen collection kits to streamline and simplify the PK collection process for single and multi-site clinical trials.

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Type Private
Industry Biotechnology
Founded 1998
Headquarters 9050 Camino Santa Fe San Diego, CA 92121 United States
Number of employees 51-200


MicroConstants, Inc. was founded in 1998 in San Diego, California by Gilbert Lam, Ph.D., a veteran in pharmaceutical development and a scientist trained in the field of pharmacokinetics. Our San Diego facility has since grown to become one of the largest bioanalytical LC/MS/MS laboratories on the West Coast of the United States, housing 15 LC/MS/MS systems and occupying 34,000 square feet of office and laboratory space.

In 2007, MicroConstants expanded its operations internationally when Dr. Lam co-founded MicroConstants China Inc. in Beijing, China. The second facility was established to meet the growing demand of pharmaceutical development being outsourced to Asia. China adopted MicroConstants’ quality systems, has been GLP compliant since April 2009, and all key personnel participated in extensive cross-Pacific training.

The laboratories in San Diego and Beijing are both fully compliant with USFDA, OECD, and MHLW Good Laboratory Practice (GLP) guidelines.


  • Drug Metabolism Assays
  • In-vitro Drug Interaction Studies
  • Protein Binding Assay
  • Method Development & Validation
  • Bioanalysis for small molecule
  • Bioanalysis for Macromolecules
  • Biomarker Assay
  • Dose Formulation Analysis
  • Impurity Characterization
  • Pharmacokinetics analysis
  • Specimen Collection kits
  • Sample storage
  • Contract Research & Site Management Services

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