Claim that Boiling Mango Leaves Cures Diabetes
WHAT IS THE TRENDING NEWS STORY
Boil These Leaves and Say Goodbye to Diabetes without Taking Any Medications!
An article discussing and explaining the preparation of mango leaves tea to fight off diabetes.
WHY THE STORY HAS MISINFORMATION
Before medications were developed by pharmaceutical companies for the treatment of diabetes, natural products were used to control elevated glucose levels, the study of these natural resources is important because of two reasons; the first one is that a large number of new drugs have been developed from them, like galegine which is a model for the synthesis of metformin and other anti-diabetic drugs and it is derived from the plant Galega officinalis; and second, because some of them are still being used in its natural form today.[1]
Artemisia annua (sweet wormwood) gave rise to artemininin, a compound which together with its analogs are now used as antimalarial therapy in many countries.[2] Paclitaxel (Taxol®), the most exciting plant-derived anticancer drug discovered in recent years, is derived from several key precursors (the baccatins) in the leaves of various Taxus species such as Taxus brevifolia.[3]
These are many herbs with strong anti-diabetic properties. Herbal treatments for diabetes have been used in patients with either insulin dependent or non-insulin dependent diabetes, diabetic retinopathy, and even in diabetic neuropathy.[4][5] A plant known as Mangifera indica, commonly known as the mango fruit, is one of these potential natural remedies. The question asked was whether this plant would actually help in managing patients diagnosed with diabetes.
To answer this question, we start with the fact that on-human studies to test the effects of Mangifera indica were limited and very small in size which make them insufficient to provide any scientific evidence.[6][7][8]
Some studies reference that the method of preparation of the mangoes extractions influences their level of anti-diabetic properties; for instance, different solvent extractions gave different inhibited potency. As an example, mango stem barks ethanolic extract showed the maximum inhibitory effects, while hexane extract showed moderate inhibitory effects and petroleum ether, chloroform and aqueous showed no inhibitory effects on alpha-amylase activities.[9] Other evidence points out that mango mature leaf preparations carry more potential to inhibit α-glucosidase versus the mango tender leaf when compared to each other.[10] The lack of specific standards at the moment of prescription and preparation is the reason why medicinal plants have not gained much importance nor scientific support.[9]
Most nutritional sites contain information like "Mangoes are good for your diabetes, "Amazing benefits of mangoes for diabetes", "Control your diabetes with Mango tea", etc. However, this information is mostly anecdotal and based on personal experiences or personal opinions that build on the above-mentioned research studies. Although mango and its extracts have received a great deal of attention because of their beneficial potential in counteracting various health conditions, at this moment there is no clear evidence to definitively prove the findings of these research studies.[11]
Finally, it is hoped that larger clinical trials are conducted, regarding the use of mango and its components for managing a variety of conditions, that lead to the discovery of potent anti-diabetic drugs for the management and treatment of diabetes.[12][13][11]
REFERENCES
- ↑ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1240543/
- ↑ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414217/
- ↑ http://pubs.acs.org/doi/abs/10.1021/acs.jnatprod.5b00617
- ↑ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609288/
- ↑ https://www.ncbi.nlm.nih.gov/pubmed/17309302/
- ↑ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155986/
- ↑ http://www.ijird.com/index.php/ijird/article/view/58574/45796
- ↑ https://www.ncbi.nlm.nih.gov/pubmed/21984455
- ↑ 9.0 9.1 http://www.greenpharmacy.info/index.php/ijgp/article/view/131
- ↑ https://www.rroij.com/open-access/invitro-enzyme-inhibition-studies-for-antidiabetic-activity-of-mature-and-tender-leaves-of-mangifera-indica-var-totapuri.php?aid=34536
- ↑ 11.0 11.1 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452255/
- ↑ http://onlinelibrary.wiley.com/doi/10.1111/bpa.12433/abstract
- ↑ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566769/