AnaBios
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| Type | Private |
| Headquarters | San Diego, CA |
| Number of employees | 11-50 employees |
AnaBios generates highly valuable, predictive human data in advance of clinical trials, ensuring the selection of the most effective and safest drugs, thereby reducing the time and expense related to clinical trial failures. Through its Phase X® technology, based on the use of human donor organs and tissues, AnaBios studies ex-vivo human responses to drugs and further investigates the molecular and functional basis of relevant human physiology.
AnaBios's research focuses primarily on the areas of high, unmet medical need, including cardiac disease and safety, pain, PKD kidney disease, and neurodegeneration. AnaBios partners and works with global Fortune 500 pharmaceutical companies, CRO's, and universities.
Located in San Diego, CA (USA), AnaBios markets its products and services directly, as well as through distributors and partners worldwide. AnaBios also drives an internal drug discovery platform via in-licensed programs from partners in the pharmaceutical industry and academia. [1]
Services
Cardiac Safety & Toxicity
Viable human heart
1. Drug-induced arrhythmia: sharp electrode recording of membrane potential for assessment of:
I. EAD
II. APD30, APD60 and APD90
III. Short Term Variability
IV. Triangulation
2. Drug-induced positive/negative inotropic effects: contraction/relaxation in ventricular trabeculae
3. Drug-induced hyper-/hypo-tension: contraction/relaxation in coronary artery rings
4. Drug-induced valvulopathy
5. Myocardial cytotoxicity
Neurotoxicity
Human DRG neurons neurotoxicity assay:
1. Cell viability
2. Apoptosis/necrosis
3. Neurite extension/degeneration [2]
5 Recent Tweets
| Date | Source | Comment |
|---|---|---|
| Oct 27 | @anabioscorp | AnaBios’ @NajahAbiGerges will present human cardiomyocyte research in SPS webinar on Nov. 2. Register here: https://goo.gl/YeK5nP
https://twitter.com/anabioscorp/status/923987509545013248 |
| Nov 13 | @anabioscorp | It’s great to be at the American Heart Association 2017 convention in Anaheim! If you’re here, don’t miss Dr. Caroline Lee from Daewoong Pharmaceuticals presenting her novel fibrosis research, utilizing AnaBios' ex vivo human cardiac platform, in room 209 at 2pm today.
https://twitter.com/anabioscorp/status/930167936559362048 |
References
Verification history
2,422 days ago
2,589 days ago
2,698 days ago- View all verifications
